Sequence Alignment with Motif Database
نویسنده
چکیده
Both sequence alignment and motif scan are e ective sequence analysis methods, which give us clews to a function of a newly determined sequence. Sequence alignment tools like FASTA [1] and BLAST [2] search for similar sequences from a sequence database and display the similarity. Motif scan tools search for sequence patterns which are already known to have some kind of functions from a motif database such as PROSITE [3]. Each method has its own limitations. Sequence alignment tools can't nd distantly related sequences. Furthermore, they do not display motifs, even if aligned sequences have common motifs. On the other hand, motif scan tools can't nd the sequence patterns which are not registered in a motif database.
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